ISSN (printed): 2154-1248. ISSN (electronic): 2154-1256.
The journal covers a broad range of aspects concerning small GTPase research, such as the cell biology and biochemistry of small GTPases, their regulators and effectors in health and disease, and will aim to publish manuscripts at the forefront of the small GTPase field. Specific topics of focus include the structural biology of small GTPases, their biochemical regulation, as well as their individual and collective cell biological functions. Processes of major interest are cell migration, cell growth, cell division, metastasis, and host-pathogen interactions. Both classical experimental approaches and more recent developments such as systems biology and bioinformatics will be considered. However, particular emphasis will be placed on work aimed at understanding the basic mechanisms underlying biological events regulated by small GTPases, at all levels from atomic structure of molecular interactions to regulation at the organismal level.
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