The field of immunotherapy is moving forward at an unprecedented rate, and a range of therapeutic approaches are now used in clinical practice, often with outstanding success. The valuable role of immunotherapy in oncology is increasingly recognized alongside conventional chemo- and radio-therapies, and the US Food and Drug Administration has approved the use of immunotherapy in melanoma, leukemias, lymphomas and myelomas, and in breast, cervical, ovarian, kidney, prostate and colorectal cancers. Immunotherapeutics are also being applied in a variety of other disease areas, including allergy, rheumatoid disease, autoimmunity and transplantation, as well as in many infections, such as HIV/AIDS and hepatitis. Many aspects of the immune system and mechanisms of immune-modulated therapies remain to be elucidated in order to exploit fully the emerging opportunities. Those involved in the research and clinical applications of immunotherapy are challenged by the huge and intricate volumes of knowledge arising from this fast-evolving field. Immunotherapy offers the scientific community an interdisciplinary forum, providing them with concise and most recent advances of various aspects of immunotherapeutics to aid navigation of this complex field.
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