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Genamics JournalSeek
Adipocyte
Adipocyte
ISSN (printed): 2162-3945. ISSN (electronic): 2162-397X.
Adipocyte deals with the recognition that the adipose tissue is the largest endocrine organ in the body, and the realization that a growing number of chronic diseases including diabetes, hypertension, cardiovascular disease and cancer are linked to dysfunctional adipose tissue. Historically, the primary function of the adipose tissue was limited to energy storage and thermoregulation. However, a plethora of research over the past 3 decades has recognized the dynamic role of the adipose tissue and its contribution to a variety of physiological processes including reproduction, angiogenesis, apoptosis, inflammation, blood pressure, coagulation, fibrinolysis, immunity and general vascular homeostasis. These pleotrophic functions of the adipose tissue are dependent on its ability to synthesize and secrete hormones, cytokines, chemokines, growth factors, enzymes, complement factors, etc, collectively called "adipokines".
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