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Frontiers in Immunology
Front Immunol

ISSN: 1664-3224.

Frontiers in Immunology promises to exert a paradigm shift in immunological publishing. It is a new and novel way to disseminate research findings and facilitate communication, both among scientists as well as the community at large. In the tradition of Sir Edward Jenner, the publishing format is “open access,” meaning that the author pays for the publication rather than the reader, so that the publication is freely available to all - worldwide. Frontiers in Immunology aims to publish the most outstanding research findings encompassing the entire field. Immunology has evolved only within the past century, and the science itself has changed from initial experiments in the first half of the 20th century using whole animals, monitoring antibody concentrations and inflammatory cutaneous reactions, to the in vitro identification, enumeration and manipulation of the various cells comprising the system in the 1960s and 1970s, to the identification of the important molecules that are responsible for directing the behavior and function of the cells in the 1980s, to genetic approaches altering the expression of the molecules in whole animals since the 1990s. As such, there is now a fairly complete picture of what happens when an antigen is introduced. However, exactly how the changes in the molecules direct changes in the cells, and how the systemic immune response is organized, regulated and orchestrated remain obscure. Thus, in immunology, the work of Linnaeus has been accomplished; now the work of Darwin begins.

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