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Clinical and Applied Immunology Reviews
Clin Appl Immunol Rev

ISSN: 1529-1049.

The Official Journal of the Association of Medical Laboratory Immunologists. Former title: Clinical Immunology NewsletterClinical and Applied Immunology Reviews (CAIR) presents timely peer reviewed articles in "mini review" and full length review format on: all aspects of the immune system in healthy subjects and patients; the indications and interpretation of testing; the development and evaluation of new immunological procedures and regulatory issues related to the development of clinical tests and the management and accreditation of diagnostic laboratories. A focus of CAIR is "bench to bedside" or how discoveries in basic immunology has or will lead to improvements in the laboratory's management of specific patient populations. Readers will find a balanced presentation of review articles which focus on theories and discoveries in the etiology, pathogenesis and diagnosis of immune mediated diseases and reviews on the development, improvement and evaluation and interpretation of clinical immunology procedures. Physicians and Laboratory Directors will find relevant updates and reviews ranging from theories of etiology and pathogensis to new laboratory methods for the diagnosis and management of patients in the disciplines of cancer immunology, neuroimmunology, autoimmunity, immune deficiency, allergy, transplantation and immunotherapy. Laboratory Directors, Managers and Technologists will find relevant reviews and evaluations of new laboratory technologies, basic science developments and laboratory compliance, accrediation and regulatory issues. Look to CAIR for: The latest discoveries in basic immunology and their potential relevance to the clinical and diagnostic immunology laboratory including: new cell surface markers, new components in cell signaling pathways, new cytokines, chemokines and their receptors The latest theories on; the immune etiology, immunopathogenesis and immunotherapy in HIV infection, cancer, autoimmunity and immunodeficiency. The latest advances in technology including: flow cytometry, molecular biology array technologies and automation; development of new vaccines, adjuvants and novel immunotherapies Recent developments in laboratory testing including; the evaluation of normal immunological parameters and functions; the diagnosis of specific infections and immune mediated diseases; monitoring of disease activity and response to therapy. The development and the results of clinical trials involving new vaccines or adjuvants; novel immunotherapy in cancer, immunodeficiency and HIV infection; immune reconstitution following anti-retroviral therapy in HIV infection and in bone marrow transplantation Clinical immunology case presentations which serve to highlight novel clinical immunology principles at the bench or the bedside

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