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Chirality
Chirality

Published/Hosted by John Wiley and Sons. ISSN (printed): 0899-0042. ISSN (electronic): 1520-636X.

The main aim of the journal is to publish scientific work on the role of molecular asymmetry in both biologically active and non-biologically active molecules in respect to their pharmacological biological and chemical properties. Drugs pesticides and other xenobiotics will be a major interest. Papers on the chemistry (physiochemical preparative synthetic and analytical) pharmacology clinical pharmacology toxicology and other biological aspects of chiral molecules will be published. Among the topics to be covered are stereospecific synthesis stereoselective analysis preparative separation of chiral molecules the influence of chirality on pharmacokinetics (absorption distribution protein binding biotransformation etc.) the influence of chirality on pharmacodynamics (drug-receptor interactions pharmacological and toxicological activity) and the influence of chirality on clinical pharmacology (therapeutic index and response bioavailability adverse drug reactions drug-drug interactions). Papers will also be published on regulatory and legal aspects in the development testing and marketing of chiral compounds. In addition to original research papers the journal will publish brief reviews short communications and conference reports. Book reviews will also appear.

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